Variations of delta waves among different sexes:
Females show more delta wave activity and are considered to be true among various mammal species. This variation is no to visible till early childhood, during the thirties or forties among humans and men exhibit decrease in activity of delta waves with increase in age when compared to female counterparts. The bigger size of skull in males is considered to be one of the affecting factors in this case, but this theory is considered to be refuted through intracranial data based on female cats that exhibit lot of delta activity.
Biochemistry and Brain Localization
Delta waves could occur in thalamus region of cortex and when related with thalamus, they generally increase in co-ordination with reticular formation. The suprachiasmatic nuclei in cortex are considered to activate delta waves since lesions in this region have considered creating commotions in delta wave activity. Apart from that delta waves also depict lateralization and there is dominance of right hemisphere when a person is sleeping. Delta waves are considered to be intermediated through T-Type calcium channels. The neurons get inhibited globally through gamma-aminobutyric acid (GABA) during delta wave sleep.
The delta activity will generally stimulate the release of various hormones which include prolactin (PRL) and GHRH which is a hormone that releases growth hormone. The secretion of prolaction that is generally associated with growth hormone is synchronized by the pituitary glands. The activity of Thyroid stimulating hormone gets decreased with response to signalling of delta waves.